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IGOB131, a novel seed extract of the West African plant Irvingia gabonensis, significantly reduces body weight and improves metabolic parameters in overweight humans in a randomized double-blind placebo controlled investigation
A review of the article by Ngondi et al., published on March 2, 2009 in Lipids and Health Disease. The article studies 102 healthy, overweight participants through 8 weeks. Half the group is dosed with 300 mg of African Wild Mango Seed Extract, and the other is dosed with a placebo. They were then evaluated at 4, 8, and 10 weeks for changes in anthropometrics and metabolic parameters.
African Wild Mango Seed Extract
African Wild Mango Seed extract is a natural health product approved by Health Canada that is derived from the the traditional West African food plant Irvingia gabonensis.
Fibre Benefits
The dietary fibre in African Wild Mango Seed Extract is water soluble and are known as "bulk forming" laxatives. Essentially, this means that it keeps the stomach from emptying, which makes you stay full longer and take a more gradual time absorbing sugars. This effect can reduce the elevation of blood sugar levels that is typical after a meal.
Cholesterol in Blood
African Wild Mango Seed extract fibre can bind to bile acids in the gut and carry them out of the body in the faeces, which causes the body to convert cholesterol into bile. This can result in the lowering of blood cholesterol as well as other blood lipids.
The Study
The study indicates that African Wild Mango Seed Extract safely and significantly reduces body weight, and impacts several metabolic parameters, including plasma adiponectin increases, and decreases in leptin and CRP levels. These changes are all associated with weight loss.
This study is cited by Health Canada as part of the research done with African Wild Mango Seed extract and its uses in supplements. Read the entire article and check out the rest of Health Canada's recommendations about the ingredient!
